

HY-15971 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-15971
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Manufacturer product page
medchemexpress.com/AMD-3465-hexahydrobromide.html
Description
AMD 3465 hexahydrobromide GENZ-644494 hexahydrobromide is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains IC50: 1-10 nM , but has no effect on CCR5-using R5 viruses.







