GENERAL CATALOGUE
AMG-424
HY-P991461 · 1 mg
MedChemExpress · Cat: HY-P991461
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medchemexpress.com/amg-424.html
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Catalog No: HY-P991461
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
AMG-424 XmAb968 is a human bispecific antibody bsAb targeting CD38 & CD3E. AMG-424 kills CD38-expressing cancer cells, triggers T-cell proliferation and attenuates cytokine release. AMG 424 has antitumor activity in a bone marrow-invasive mouse cancer model and induces peripheral B-cell depletion in cynomolgus monkeys. AMG-424 can be used in multiple myeloma research. Recommended isotype control: half-IG G1-kappa/ scFv-heavy-lambda -h-CH2-CH3.
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