GENERAL CATALOGUE
Aminopterin
HY-14518 · 5 mg
MedChemExpress · Cat: HY-14518
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Catalog No: HY-14518
CAS No: 54-62-6
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
Aminopterin 4-Aminofolic acid , the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase DHFR with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia.
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