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Amivantamab (FUT8-KO)
GENERAL CATALOGUE

Amivantamab (FUT8-KO)

HY-P9977A · 1 mg

MedChemExpress · Cat: HY-P9977A

₹440 – ₹650 approx.This price excludes freight and taxes. Please RFQ to get the final price.

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Catalog No: HY-P9977A
Category: JAK STAT Signaling
Pack Size: 1 mg
Brand: MedChemExpress

Description

Amivantamab FUT8-KO is an anti-EGFR-MET monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene FUT8 knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Amivantamab FUT8-KO inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer cells.

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