GENERAL CATALOGUE
Amonafide dihydrochloride
HY-10982A · 50 mg
MedChemExpress · Cat: HY-10982A
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Catalog No: HY-10982A
CAS No: 150091-68-2
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
Amonafide dihydrochloride AS1413 dihydrochloride is a topoisomerase II Topo II inhibitor and DNA intercalator with activity in inducing apoptotic signaling. Amonafide dihydrochloride can inhibit the binding of Topo II to DNA, thereby preventing the synthesis of DNA and RNA. Amonafide dihydrochloride maintains cytotoxic activity in the presence of P-glycoprotein-mediated multidrug resistance MDR .
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