

HY-128204 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-128204
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medchemexpress.com/an3661.html
Description
AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 PfCPSF3 . AN3661 inhibits Plasmodium falciparum laboratory-adapted strains mean IC50=32 nM , Ugandan field isolates mean ex vivo IC50=64 nM , and murine P. berghei and P. falciparum infections.