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Anemarsaponin B
GENERAL CATALOGUE

Anemarsaponin B

HY-N0811 · 1 mg

MedChemExpress · Cat: HY-N0811

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Catalog No: HY-N0811
CAS No: 139051-27-7
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress

Description

Anemarsaponin B is a steroidal saponin. Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-?B by blocking the phosphorylation of I?B?. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 MKK3/6 and mixed lineage kinase 3 MLK3 . Anti-inflammatory effect .

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