Angiotensin II (1-4), human TFA

Description

Angiotensin II 1-4 , human TFA is an endogenous peptide produced from AT I by angiotensin-converting-enzyme ACE . Angiotensin II binds the AT II type 1 AT1 receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney.