GENERAL CATALOGUE
Annonacin
HY-N2877 · 1 mg
MedChemExpress · Cat: HY-N2877
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medchemexpress.com/annonacin.htmlCatalog No: HY-N2877
CAS No: 111035-65-5
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Annonacin is an acetylgenin that is toxic by inhibiting the pathway of the mitochondrial complex. Annonacin increases tau phosphorylation in R406W+/+ mice. Annonacin acts as an inhibitor of the sodium/potassium and sarcoplasmic reticulum SERCA ATPase pumps. Annonacin has significant killing effect on ovarian cancer cell, cervical cancer cell, breast cancer cell, bladder cancer cell and skin cancer cell. Annonacin induces apoptosis through Bax and Caspase-3-related pathways.
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