Antalarmin hydrochloride (Standard)

Description

Antalarmin hydrochloride Standard is the analytical standard of Antalarmin hydrochloride . This product is intended for research and analytical applications. Antalarmin hydrochloride is an oral active non-peptide corticotropin-releasing hormone receptor 1 CRHR1 antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory effects in arthritis models, and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.