Anti-alpha-1 Antitrypsin Antibody

Description

Alpha-1 Antitrypsin is a secreted serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Its aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Thus, defects in this gene can cause emphysema or liver disease.