Anti-MRSA agent 20

Description

Anti-MRSA agent 20 Compound a4 is an anti-microbial agent MIC: 0.03125 ?g/mL against MRSA . Anti-MRSA agent 20 binds to the ribosomal peptidyl transferase center and inhibits bacterial survival by inhibiting MRSA toxin synthesis and bacterial division. Anti-MRSA agent 20 significantly reduces the MRSA load in the lungs and attenuates lung injury in the MRSA-infected mice ED50 = 6.48 mg/kg .