

Y058156 · 100 uL
abm good · Cat: Y058156
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abmgood.com/anti-parp1-antibody-y058156.htmlDescription
This gene encodes a chromatin-associated enzyme, poly ADP-ribosyl transferase, which modifies various nuclear proteins by poly ADP-ribosyl ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes


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