Anti-PDK1 (Ab-241) Antibody

Description

Pyruvate dehydrogenase PDH is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase PDK results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Jun 2013