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Anti-Smad7 Antibody
GENERAL CATALOGUE

Anti-Smad7 Antibody

Y058362 · 100 uL

abm good · Cat: Y058362

₹200 – ₹310 approx.This price excludes freight and taxes. Please RFQ to get the final price.

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Catalog No: Y058362
Category: General Materials
Pack Size: 100 uL
Brand: abm good

Description

The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 TGFBR1 , leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 CRCS3 . Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jun 2010

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