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Anti-TAX1BP2 Antibody
GENERAL CATALOGUE

Anti-TAX1BP2 Antibody

Y030163 · 100 ug

abm good · Cat: Y030163

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Catalog No: Y030163
Category: General Materials
Pack Size: 100 ug
Brand: abm good

Description

TAX1BP2 was initially identified as a novel centrosomal protein that interacts directly with the human T-cell leukemia virus type 1 HTLV-1 -encoded oncoprotein, Tax, and inhibits centrosome overduplication. Subsequently, TAX1BP2 was found to be a tumor suppressor in hepatocellular carcinoma, and accumulation of TAX1BP2 was observed upon chemotherapeutic drug treatment. Here, we provide evidence that TAX1BP2 is a direct phosphorylation substrate of ATM. The protein level of TAX1BP2 is significantly upregulated in response to DNA damaging agents.

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