Anti-TYK2 (Ab-1054) Antibody

Description

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases JAKs protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome HIES - a primary immunodeficiency characterized by elevated serum immunoglobulin E. provided by RefSeq, Jul 2008