

Y058683 · 100 uL
abm good · Cat: Y058683
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abmgood.com/anti-zgpat-antibody-y058683.htmlDescription
Transcription repressor that specifically binds the 5-GGAG GA A GA A-3 consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.


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