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Anticancer agent 157
GENERAL CATALOGUE

Anticancer agent 157

HY-149523 · 50 mg

MedChemExpress · Cat: HY-149523

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Catalog No: HY-149523
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

Anticancer agent 157 compound 15 is a NO inhibitor IC50=0.62 ?g/mL with anti-inflammatory and anticancer activities. Anticancer agent 157 can bind to iNOS inducible NO synthase and caspase 8, causing nuclear fragmentation and chromatin condensation, inducing apoptosis. Anticancer agent 157 inhibits HT29 colon cancer cells IC50=2.45 ?g/mL , Hep-G2 liver cancer cells IC50=3.25 ?g/mL , and B16-F10 murine melanoma cells IC50=3.84 ?g/mL .

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