

HY-149958 · 50 mg
MedChemExpress · Cat: HY-149958
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medchemexpress.com/antileishmanial-agent-17.html
Description
Antileishmanial agent-17 is a coumarin hybrid compound with antileishmanial effects IC50 <0.78 ?M . Antileishmanial agent-17 is safe to normal VERO cells. Antileishmanial agent-17 binds to folate pathway enzymes pteridine reductase and DHFR-TS. And Antileishmanial agent-17 shows the most potent with IC50 value of 0.40 ?M against promastigote and 0.68 ?M against amastigote, respectivley.







