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Antileishmanial agent-19
GENERAL CATALOGUE

Antileishmanial agent-19

HY-155520 · 5 mg

MedChemExpress · Cat: HY-155520

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Catalog No: HY-155520
Category: Anti-infection
Pack Size: 5 mg
Brand: MedChemExpress

Description

Antileishmanial agent-19 Compound F27 is an antileishmanial agent, with a IC50 of 3.39 ?M for L. donovani promastigotes. Antileishmanial agent-19 inhibits Leishmania prolyl-tRNA synthetase. Antileishmanial agent-19 inhibits host PI3K/Akt/CREB axis-mediated IL-10 secretion. Antileishmanial agent-19 induces autophagy-mediated apoptosis in L. donovani promastigotes. Antileishmanial agent-19 reduces parasite burden in L.d-infected animals.

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