GENERAL CATALOGUE
Antileishmanial agent-21
HY-155845 · 50 mg
MedChemExpress · Cat: HY-155845
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medchemexpress.com/antileishmanial-agent-21.htmlCatalog No: HY-155845
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Antileishmanial agent-21 compound 4e is an antileishmanial agent that targets the Leishmania pteridine reductase 1 Lm-PTR1 . Antileishmanial agent-21 has an anti-folate mechanism, and folic acid and leucovorin can reverse the anti-leishmanial activity of Antileishmanial agent-21. Antileishmanial agent-21 inhibits the Chloroquine HY-17589A -resistant strain of Plasmodium falciparum RKL9 with an IC50 of 0.0198-0.096 ?M.
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