GENERAL CATALOGUE
Antimalarial agent 38
HY-157892 · 1 mg
MedChemExpress · Cat: HY-157892
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Catalog No: HY-157892
CAS No: 123580-46-1
Category: Anti-infection
Pack Size: 1 mg
Brand: MedChemExpress
Description
Antimalarial agent 38 is an orally active antimalarial agent, which inhibits Plasmodium falciparum D6 strain, Chloroquine HY-17589A -sensitive Thai strain and Chloroquine-resistant FcB1 strain and K1 strain, with IC50s of 0.5, 13, 1 and 13 ?M, respectively. Antimalarial agent 38 is non-cytotoxic for mammalian cells MCR58 IC50 140 ?M. Antimalarial agent 38 improves the survival rate of Plasmodium yoelii nigeriensis infected mouse model.
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