Antimicrobial agent-39

Description

Antimicrobial agent-39 Compound 8i is an antibiotic that targets 50S ribosomal subunit and inhibits bacterial protein synthesis. Antimicrobial agent-39 disrupts bacterial cell membranes, leads to leakage of cell contents, thereby exhibiting board-spectrum actibacterial activity. Antimicrobial agent-39 targets organic cation transporters OCTs , accumulates in infected kidneys, thereby ameliorating pyelonephritis in mouse models.