GENERAL CATALOGUE
Antiproliferative agent-53-d3
HY-163816 · 1 mg
MedChemExpress · Cat: HY-163816
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medchemexpress.com/antiproliferative-agent-53-d3.htmlCatalog No: HY-163816
CAS No: 2923508-77-2
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress
Description
Antiproliferative agent-53-d3 Compound C1 is an inhibitor for theta-mediated end joining TMEJ in HEK293 cell with an IC50 of 0.14 AAasAasAAmuM. Antiproliferative agent-53-d3 is the inhibitor for CYP2C19 and CYP2C9 with IC50 of 0.77 and 3.1 AAasAasAAmuM. Antiproliferative agent-53-d3 inhibits the proliferation of DNA repair-compromised cells, with IC50 of 8.1 AAasAasAAmuM for BRCA2-/- DLD-1. Antiproliferative agent-53-d3 exhibits good pharmacokinetic characteristics in CD-1 mice.
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