Antitumor agent-156

Description

Antitumor agent-156 Compound 20 causes DNA damage and mitochondrial dysfunction, promotes reactive oxygen species generation, activates endoplasmic reticulum stress, and induce apoptosis, autophagy and ferroptosis. Antitumor agent-156 shows superior antitumor activity against cancer cells including Cisplatin HY-17394 resistance cells. Antitumor agent-156 displayS good liver-targeting ability.