GENERAL CATALOGUE
Antitumor agent-170
HY-162644 · 50 mg
MedChemExpress · Cat: HY-162644
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Manufacturer product page
medchemexpress.com/antitumor-agent-170.htmlCatalog No: HY-162644
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
Antitumor agent-170 Compound C6 exhibits inhibitory activities against PD-1/PD-L1 interaction and PARP7, with IC50 of 0.342 ?M and 7.05 nM. Antitumor agent-170 exhibits a high affinity to human PD-L1, with a Ki of 9.31 nM. Antitumor agent-170 restores the T cell function and increases IFN-? secretion. Antitumor agent-170 exhibits antitumor efficacy against melanoma in mouse models and good pharmacokinetic characteristics.
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