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Antitumor agent-60
GENERAL CATALOGUE

Antitumor agent-60

HY-146432 · 50 mg

MedChemExpress · Cat: HY-146432

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Catalog No: HY-146432
CAS No: 865784-65-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

Antitumor agent-60 compound 20 is a potent antitumor agent, targeting RAS-RAF signaling pathway and binding to CRAF with a Kd value of 3.93 ?M. Antitumor agent-60 induces apoptosis by blocking cell cycle at G2/M phase. Antitumor agent-60 enhances the level of p53 and ROS. Antitumor agent-60 causes oval and irregular nucleus in cancer cells. Antitumor agent-60 can suppress the growth of tumor to some extent in A549 xenograft model.

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