GENERAL CATALOGUE
Apatinib-d8 free base
HY-13342AS · 1 mg
MedChemExpress · Cat: HY-13342AS
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medchemexpress.com/apatinib-d8-free-base.htmlCatalog No: HY-13342AS
CAS No: 2468771-43-7
Category: Autophagy
Pack Size: 1 mg
Brand: MedChemExpress
Description
Apatinib-d8 free base is the deuterium labeled Apatinib free base. Apatinib free base YN968D1 free base is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 IC50=1 nM . Apatinib free base YN968D1 free base is an anti-angiogenic drug for the research of advanced or metastatic gastric cancer. Apatinib free base YN968D1 free base potently inhibits Ret, c-Kit and c-Src with IC50s of 13, 429 and 530 nM, respectively. It also inhibits cellular phosphorylation of VEGFR-2, c-kit and PDGFR?.