APEX1 Mouse Monoclonal Antibody

Description

EnkiLife offers the APEX1 Mouse Monoclonal Antibody. This antibody reacts with Human,Rat,Monkey species and is suitable for WB,IHC,ELISA,FC application. Alternative Names of Immunogen: APE; APX; APE1; APEN; APEX; HAP1; REF1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.