GENERAL CATALOGUE
APG-2449
HY-155163 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-155163
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Manufacturer product page
medchemexpress.com/apg-2449.htmlCatalog No: HY-155163
CAS No: 2196186-84-0
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
APG-2449 is an orally active inhibitor for BCL-2 and multikinase ALK/FAK/ROS1 with potent antitumor activities. APG-2449 reduces cell viability and enhances apoptosis in acute myeloid leukemia cells in vitro. APG-2449 decreases activation of FAK and its downstream effectors. APG-2449 can be studied in research for mesothelioma tumor, non-small cell lung cancer, ovarian cancer, hematologic and solid malignancies.
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