Apixaban Ester Impurity

Description

Impurity in commercial preparation of Apixaban. Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 2011 ; Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 2011 ; barrett, Y.C. et al.: Thromb. Haemos., 105, 181 2011 ;