GENERAL CATALOGUE
APJ receptor agonist 4
HY-145284 · 50 mg
MedChemExpress · Cat: HY-145284
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medchemexpress.com/apj-receptor-agonist-4.html
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Catalog No: HY-145284
CAS No: 2762567-70-2
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
APJ receptor agonist 4 is a potent and orally active agonist of apelin receptor APJ with EC50 and Ki of 0.06 nM and 0.07 nM respectively. APJ receptor agonist 4 displays excellent pharmacokinetic profiles in the rodent heart failure HF model. APJ receptor agonist 4 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 4 leads to improved cardiac function and can be used for researching the HF disease.