GENERAL CATALOGUE
APJ receptor agonist 5
HY-145285 · 5 mg
MedChemExpress · Cat: HY-145285
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medchemexpress.com/apj-receptor-agonist-5.html
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Catalog No: HY-145285
CAS No: 2135514-20-2
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
APJ receptor agonist 5 compound 3 is a potent and orally active agonist of apelin receptor APJ with an EC50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure HF model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease.
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