APOA1 hFc Chimera, Human

Description

Apolipoprotein A1 ApoA1 is a main protein moiety in high-density lipoprotein HDL particles. Generally, ApoA1 and HDL are considered as atheroprotective. In prooxidant and inflammatory microenvironment in the vicinity to the atherosclerotic lesion, ApoA1/HDL are subjected to modification. The chemical modifications such as oxidation, nitration, etc result in altering native architecture of ApoA1 toward dysfunctionality and abnormality.