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Apostatin-1
GENERAL CATALOGUE

Apostatin-1

HY-134050 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-134050

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medchemexpress.com/apostatin-1.html
Catalog No: HY-134050
CAS No: 2559703-06-7
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Apostatin-1 Apt-1 is a potent TRADD inhibitor. Apostatin-1 can bind with TRADD-N KD=2.17 ?M , disrupting its binding to both TRADD-C and TRAF2. Apostatin-1 modulates the ubiquitination of RIPK1 and beclin 1. Apostatin-1 blocks apoptosis and restores cellular homeostasis by activating autophagy in cells with accumulated mutant tau, ?-synuclein, or huntingtin.

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