GENERAL CATALOGUE
Apricitabine
HY-14913 · 1 mg
MedChemExpress · Cat: HY-14913
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Catalog No: HY-14913
CAS No: 160707-69-7
Category: Anti-infection
Pack Size: 1 mg
Brand: MedChemExpress
Description
Apricitabine SPD754; AVX754 , the - enantiomer of 2?-deoxy-3?-oxa-4?-thiocytidine dOTC , is a highly selective and orally active HIV-1 reverse transcriptase RT inhibitor Ki=0.08 ?M , as well as inhibits DNA polymerases ?, ?, and ? with Ki value of 300 ?M, 12 ?M, and 112.25 ?M, respectively. Apricitabine SPD754; AVX754 shows promising antiretroviral efficacy, good tolerability and a low propensity for resistance selection in antiretroviral-naive HIV infection 2 .