

HY-15895 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-15895
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Manufacturer product page
medchemexpress.com/ACT-132577.html
Description
Aprocitentan ACT-132577 is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively. Aprocitentan is an antihypertensive agent.







