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Aprutumab ixadotin
GENERAL CATALOGUE

Aprutumab ixadotin

HY-141600 · 1 mg

MedChemExpress · Cat: HY-141600

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Catalog No: HY-141600
CAS No: 1708947-48-1
Category: Antibody-drug Conjugate ADC Related
Pack Size: 1 mg
Brand: MedChemExpress

Description

Aprutumab ixadotin BAY 1187982 is the first antibody-drug conjugate ADC to target FGFR2 and the first to use Auristatin-based payload. Aprutumab ixadotin contains a fully human anti-FGFR2 monoclonal antibody Aprutumab HY-P99007 conjugated by lysine side chains to a non-cleavable linker and via this an innovative Auristatin W derivative. Aprutumab ixadotin can be used for the study of advanced solid tumors, such as FGFR2-positive gastric cancer and triple-negative breast cancer.

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