GENERAL CATALOGUE
APY29
HY-17537 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-17537
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Catalog No: HY-17537
CAS No: 1216665-49-4
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
APY29, an ATP-competitive inhibitor, is an allosteric modulator of IRE1? which inhibits IRE1? autophosphorylation by binding to the ATP-binding pocket with IC50 of 280 nM. APY29 acts as a ligand that allosterically activates IRE1? adjacent RNase domain.