GENERAL CATALOGUE
AR-42
HY-13265 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13265
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Catalog No: HY-13265
CAS No: 935881-37-1
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
AR-42 HDAC-42; OSU-HDAC42 is a potent, orally bioavailable pan-HDAC inhibitor IC50=16 nM . AR-42 induces growth inhibition, cell-cycle arrest, apoptosis, and activation of caspases-3/7. AR-42 promotes hyperacetylation of H3, H4, and alpha-tubulin, and up-regulation of p21. AR-42 shows cytotoxicity against various human cancer cell lines.
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