GENERAL CATALOGUE
Arenobufagin
HY-N0876 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N0876
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medchemexpress.com/Arenobufagin.html
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Catalog No: HY-N0876
CAS No: 464-74-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Arenobufagin is a natural bufadienolide that can be extracted from toad venom. Arenobufagin can induce apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway. Arenobufagin has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2/ADM cells. Arenobufagin can inhibit VEGF-mediated angiogenesis through suppression of VEGFR-2 signaling pathway.
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