GENERAL CATALOGUE
Arenobufagin (Standard)
HY-N0876R · 50 mg
MedChemExpress · Cat: HY-N0876R
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medchemexpress.com/arenobufagin-standard.html
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Catalog No: HY-N0876R
CAS No: 464-74-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Arenobufagin is a natural bufadienolide that can be extracted from toad venom. Arenobufagin can induce apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway. Arenobufagin has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2/ADM cells. Arenobufagin can inhibit VEGF-mediated angiogenesis through suppression of VEGFR-2 signaling pathway.
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