ARG1 (7H3) Rabbit Monoclonal Antibody

Description

EnkiLife offers the ARG1 (7H3) Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,IP,IF-P application. Alternative Names of Immunogen: ARG1; Arginase-1; Liver-type arginase; Type I arginase; Arginase liver; Liver Arginase;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:5000,IHC 1:200-1:500,IP 1:10-1:100,IF-P 1:200-1:500 Background: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.