Arg2 Rabbit Monoclonal Antibody

Description

EnkiLife offers the Arg2 Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,ICC/IF,FC application. Alternative Names of Immunogen: Arginase II; Kidney-type arginase; Non-hepatic arginase; Type II arginase. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:5000,ICC/IF 1:200-1:500,FC 1:50-1:100 Background: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]