Argonaute 2 Antibody, mAb, Rabbit

Description

Required for RNA-mediated gene silencing RNAi by the RNA-induced silencing complex RISC . The minimal RISC appears to include AGO2 bound to a short guide RNA such as a microRNA miRNA or short interfering RNA siRNA . These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing.