GENERAL CATALOGUE
ARI-1
HY-139534 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-139534
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medchemexpress.com/ari-1.html
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Catalog No: HY-139534
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ARI-1 is a receptor tyrosine kinase-like orphan receptor 1 ROR1 inhibitor. ARI-1 blocks the PI3K/AKT/mTOR signaling pathway in a ROR1-dependent manner. ARI-1 upregulates cleaved-PARP and p-P38. ARI-1 induces Apoptosis. ARI-1 has anticancer activity against non-small cell lung cancer.
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