GENERAL CATALOGUE
Aristolactam I
HY-N2013 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N2013
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Catalog No: HY-N2013
CAS No: 13395-02-3
Category: Cytoskeleton
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-?/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis.
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