GENERAL CATALOGUE
ARN-21934
HY-137466 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-137466
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Catalog No: HY-137466
CAS No: 2230854-93-8
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ARN-21934 is a potent, highly selective, blood-brain barrier BBB penetrant inhibitor for human topoisomerase II ? over ?. ARN-21934 inhibits DNA relaxation with an IC50 of 2 ?M as compared to the anticancer agent Etoposide IC50=120 ?M . ARN-21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research.
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