GENERAL CATALOGUE
ARN14494
HY-115498 · 5 mg
MedChemExpress · Cat: HY-115498
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Catalog No: HY-115498
CAS No: 1037837-27-6
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
ARN14494 is a potent and selective serine palmitoyltransferase SPT inhibitor, with an IC50 of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from ?-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti-apoptosis, and anti-inflammation. ARN14494 can be used for AlzheimerAAasAasAas disease research.
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